This project is devoted to the theoretical and experimental study of electron scattering off medium-mass nuclei (¹²C, ¹⁶O, and ⁴⁰Ca) with the goal of improving our understanding of the nuclear structure dynamics governing lepton-nucleus cross sections. This effort will allow us to quantify and possibly reduce uncertainties stemming from nuclear structure, which presently affect the extraction of neutrino oscillation parameters from long-baseline experiments.